RE: amount of charge
All rifles are different. I have a friend that shoots a Traditions .50 caliber Kentucky long rifle and I swear, any powder charge he wants to shove down it will shoot accurate. Then I have some rifles that are real fussy about powder charges. A couple of them are down right demanding. My CVA Staghorn likes 90 grains of powder. My Knight Wolverine seems to do best with 80-85 grains of powder. My Black Diamond XR on the other hand shoots about anything I want to shoot.
The easy way is start them out around 80 grains with a quality sabot load for the inlines or if the rifle is a conicals shooter then pick a conical. Then shoot groups. Add powder of about 5-10 grains and shoot a group. Keep doing that until your group falls apart and starts to spray them all over, then back off just a little to the best group or the powder charge you feel comfortable with.
Also besides the rifle, the kind of powder and projectile can also make a big difference. When I shoot Pinnacle for instance, nothing bigger then 300 grains for a projectile. When I shoot heavy, then I like Triple Se7en or a 3f powder.
All you can do is experiment. That is what makes these rifles so much fun. For instance, I was shooting a CVA Stalker Carbine .50 caliber today with a 1:32 twist. I shot a couple of conicals and accuracy was all right but I felt could be better. Just for kicks, I put in some 240 grain Thompson Center Cheap Shots and 80 grains of 2f Black Powder. All of a sudden that little carbine was showing some real potential. So I tried some 245 grain Buffalo BulletBallets. And again, the rifle shot them well. So even though I am sure there is a heavy conical out there it will shoot well, I do know that it will shoot lighter stuff real good. All of it is a game of experimentation.