RE: Signs of pressure?
Yea, it will work, but RL22 might be better for your two magnums. Or H4831sc.
I use 4350 for my 270win.
Don't worry about about most accurate loads and stuff in your manual. Doesn't mean a thing. You have going to see alot of differences between manual to manual.
Just make note of your bolt lift, study your primers after every shot. And work up in 1gr increments for most bullets like SST, partitions, Bullistic tips, and gamekings, but be careful with barnes X, failsafes, TSX's, and bonded bearclaws. They will build pressure quick and unexpected. Really need a barnes manual for these. Start 10% down.