If you're talking about just barely moving the nocking point to clean up an almost perfect paper hole, then I can go along with making a small tiller adjustment. If you're talking about moving the nock point 1/8" or more, leave tiller alone and move the nock point.

Personally, I don't mess with my tiller once I get it where I want it. I make all my tuning adjustments with the rest and nock point. It's a little more effort to do it that way, but I want it right.

Also, I get my cams timed and/or synchronized by twisting the cables instead of messing with tiller. We had to do that tiller thing to some degree back in the days of steel cables, but it's not necessary any more. You can now have perfect tiller AND perfect timing if you want it.