I dont have any solid proof about the blood vessel theory, I just remember posting this question when I had first joined and that was the general conclusion.

I have never shot/found a buck with that big of a hole in the antler. I have noticed though that the holes varry in size.

One thing that hasn't been brought up is the depth of the hole. If it only goes down an inch and abruptly stops, then I wouldlean more towardsthe bug theory Because if it were the remnance of a blood vessel, then why would only thatinch of the cavity be left open?