Which ever bullet your rifle likes better, as they are both up to the task you have in mind and excellent bullets. I am a nosler fan but when it comes to moose and elk the TSX is now my bullet of choice. I personally use a light for grain bullet - 140gr TSXin my 7mm rem mag and it performance has been IMPRESSIVE/text book. I like the fact it pentrates/retains weight while still creating a good wound channel and wastes minimal meat on raking or shoulder shots. Accuracy has been superb with the tsx to boot. Only recovered one TSX bullet thus far from a bull moose and expansion was over double the diameter with weight retention in excess of 90%, this after busting the opposite shoulder of a bull moose at high MV. 3 Bull elk and another bull moose were pass thru's, making up the rest of the game accounted for with the 140 TSX for me personally(all casesproduced torched vitals and animals well within 100 yards after the single hits).