I am very partial to large bore single action Rugers. Safe, strong, and not extremely expensive... 44 Magnum if you don't reload. I would do 45 Colt (aka Long Colt) if you reload. You can shoot quite a few rounds without wearing out. 44 Maggie comes off the shelf with a wide range of available bullet weights. For a reeeeeeally long time the 357 Magnum was the only plussed up revolver load and some did hunt all the North American game with it. But the big bores do it so much better. Also, get at least a 6" barrel. Take advantage of the extra velocity.