You may be right about the .375 H&H, but I'd like to know where your information comes from, as I have never seen an exhaustive compilation of statistics on what calibers have beenmost used in Africa since firearms were first used to kill rhino, Cape Buffalo, elephant, hippo, lion and leopard. A great many such beasts have been slain with large bore, rouind-ball firing muzzleloaders, as well as cartridge arms. I suspect you'd be surprised to know how much big/dangerous game whas been killed with the lowly .303 British!