Those 2 rounds are not comparable. The 17 has alot more power. The 17 HMR and the 22 Mag are comparable. The 17 Mach 2 and the 22 LR are comparable. Id say get the 17 HMR or a 22 Mag but thats just my opinion. I have both and would recoment a 22 Mag before the 17 HMR. They both are accurate enough to shoot 100 yards but the 17 bullet has alot of wind drift past 125 yards. Also the 22 Mag has alot more knock down power out to 200 yards then the 17 HMR.