While I would probably shoot, because I am confident out to that range for targets, I certainly can see reasons not to shoot like early in stated.
Many guys wouldn't have a prayer at hitting a 50 yd shot. If you gut shot the deer, it WILL die, and the less its pushed, the CLOSER it will die to you. If you have a non pressured area, and know it well, you should find any gut shot deer. Now if you are chancing that 2nd shot, are you going to make the deer run much farther than it otherwise would have? Will it cross property lines(which we all know the debate that stirs)?