In most cases the 60 lb bow maxed out will be slightly more effecient. Probably differs from manufacturer and cam types though. Would it be enough to notice? I doubt it.
As far as being smoother to draw, I don't know but it would be simple enough to check. Go to a mathews dealer and shoot both bows set up that way. Heck you can check the speed while your at it too. If you do it let us know what happens.
I will give you my opinion though. If are not planning on shooting over 60 lbs don't get the 60-70 lb bow. Get the 50-60 lb bow and set it at 55 lbs. Then when you choose arrows get them spined for 55 lbs and when you go to fine tune the bow you have 5 lbs in either direction to get your spine perfect. If you get the 60-70 bow and shoot it at 60 your only recourse is to turn it up. And this may hurt your shooting more than help it. Never get a bow with a max weight higher than you intend to shoot, it's just a waste. Not to mention a temptation to shoot more poundage than you probably should.
With the newer bows on the market and an average draw length there is just no need to shoot more than 50 or 60 lbs at deer sized game at 30 yards and in.
I have a little story for you (imagine that, me with a story

).
My buddy has an older Darton Maverick. Probably early 90's with eccentrics and steel cables. This was a fast bow for the time it was made. He has killed many deer with it. He shoots 28 inches of draw at 73 lbs! When I got my Darton Yukon in 2,000 we took them to a shop and shot them side by side. My newer bow with the CPS cams shot the same arrow a bit faster than his did, but mine was set up with 26 inches of draw and a bit under 60 lbs of draw weight.
Not to mention my Yukon was smaller, lighter, more quite and had much less hand shock and recoil. And 75% let off, I think his is around 60%.
Now I have 2004 mighty might by bowtech and it will blow my darton out of the water, let alone his old maverick. And it will do it with virtually no noise and no recoil at all! This bow will darn near do what his will at 50 some lbs of draw weight and 2 inches less draw length. And it's 31 inches long with 80% let off!! I believe his bow is like 41 inches long and weighs around 6 lbs.
After shooting my bowtech he started saving up money and got a newer PSE. He seems pretty happy with it. I think he shoots it at 65 lbs. So he almost halved his draw weight and greatly reduced his holding weight, and probably increased his speed quite a bit too. I think he could have gotten away with 60 lbs but he is stubborn

.
Paul