The Rifleman gave you a good answer-you have to develop Your load for Your rifle, using Your component set. NATURALLY, you ALWAYS START with the lowest recommended load, that way you seldom get into trouble due to a change of one or more of the components (lke using WIN instead of REM primers.....)

I have had great results shooting black bears with the Nosler Partition bullet. I understand that their Accubonds are just as good!