There are some pretty savvy guys on this board who shoud be able to help you. Info about the arrows you are shooting, and the specs of your Dren would be most helpful. Shoot throughs may be a little less forgiving than a drop away, but the shoot through should be tunable and do a good job. You could have fletching contact. When your shots are off, is there a direction they are going, or is there no pattern? More info is needed for people to be able to help you. I guess the best thing would be to take it back to the shop where you bought it, since Mathews bows are pro shop only. The shop that sold you the bow should be able to help you out.