If you shoot for the neck, behind the ear, there's no way the deer's going to run off, there's not much neck there, and if people can kill deer with .22 Hornet at the base of the neck, a .308 will really knock 'em out.
My hunting buddies shoot deer in the head/neck, and the deer have never run. One of them uses a 25-06, and a .357 Levergun. I would never, take a shot for the head or neck if it's beyond 100 yards, otherwise, it's shoulder shot time.


And MO Hoyt, quit trying to impose bowhunting shots on gun hunters, if you can't hit a deer with a head or neck shot, don't automatically say I or other hunters can't.