I f useing the 243 that and the 87 hornadyBTHP is what I use on deer,have taken deer 300 yds+ with both.Let a buddy use the 243 with 85 gr sierra's this past year and he dropped his first long distant deer at 270 yds.Shot just behind the shoulder complete pass through,went about 30 yds pilled up.Let one brother use it the year before and he dropped 3 or 4 with the same load.