ORIGINAL: SwampCollie

There is no disadvantage other than you have fewer pellets, which translates to fewer chances to get that critcal brain/spine hit. I know of a few 12 2 3/4" guns that will kill turkeys dead all day at 40 yards, but most are best kept inside of 35.

It really depends on your gun. There is no disadvange is pellet energy or anything like that. You get less recoil, for less money, and as long as your gun/choke shoots them well... then its a great way to go.