I think string jumping has way more to do with the animal than the bow. If the animal is standing alert and looking/listening in your direction, he is probably going to drop the instant you touch the trigger. As some have said, you might still hit them, but the chances of a bad hit or miss are much greater.

I have hunted many times with little or no silencing equipment on my bow and if the animal is relaxed, they don't move before the arrow gets there.

I let the animal determine how I aim also. If a deer catches movement or hears me draw and goes on alert. I aim at the lower 1/3 and wait for the head bob to release. If deer is still relaxed when I reach full draw, I aim dead center.