RE: how many shots
If everybody thought one shotand then educated themselves on what that takes and then trained themselves to do it and then disaplined themselves to take only the shot that would do it with the cartridge and load their using; the 22 Hornet would fill the bill with one shot. Of course I don't recommend that but if you throw in chosing a cartridge and a bullet designed to suceede from reasonable angles, I can think of some I would do it with that might seem awfully small to some. How small? Well for anything over the size of a deer, I concider anything under 26 cal to small.