17HMR for squirrels and rabbits- deadly accurate and quiet!
.223 Rem for 'yotes to 350 yds
.243 Win for 'yotes past 350
The distance and terrain you hunt for 'yotes will determine your caliber choice.
Heck, if you can hunt 'yotes close, the 17HMR and head/neck shots will drop 'em where they stand! (75yds or less)
A 12ga with BBB or T shot is also good out to 50 yds.