the 260rem would be a better round for deer and yotes. smaller bullet and light to nothing recoil.good out to 250yds.( depending on what you hunt

as for the 280rem bigger bullets. more recoil and good as far as you can shoot.

also you will find more companies have guns in the 280rem selection compared to the 260rem.

i would of bought a 260rem in a heartbeat if browning still made them in their line.