I would take the .338 Win Mag over the others you mentioned. Top it off with a Leupold VX II 0r III in 3x9 and you're set to shoot close in the trees at 3 power or 400 yds across a meadow at 9 power for the animal of a lifetime. If you're up to doing your part, the .338 WM will never let you down.
Reasons: Excellent accuracy, good ballistics, great knock down power, ammo readily available even in a Mom and Pop general sporting goods store becuase of it's popularity, and can kick a big bear's butt if you happen to run into a bad situation while hunting for elk, moose or bears, etc.
I have one in a Ruger No 1 and love it!

Go on a hunt and tell your guide you're totin' a 30-06 along for Yukon Moose or any big bears and he'll likely question your choice. Tell him you're bringing along a .338 WM and he'll nod and move on to the next topic!