Ditto on the 70/460 combo. Plenty of punch left at 100 for North American big game.

Guessing that's a 6" circle and a 3" group. Nothing shabby about that Conicaloader. I'll be very impressed if you can work that combo onto the target face 6/6 @ 100. That would be a fine hunting-ready base and you can experiment from there. Great start. Want to sell that scope!