I have used the 180 gr. Speer Grand Slam with great success in this caliber. Seat it out to 2.800" andtry WW 748 powder. Youshould be able to get over 2700 fps in a 24" barrel. I believe Speeralso loadsthis in a factory offering called "Nitrex" ammunition. This bullet will kill elk, bear,and moose real well as long as the distance is not extreme. May be a little overkill, in terms of penetration, for deer. I like 165 Ballistic Tips for deer in this caliber, but if you want to load one bullet for everything I would go with the GS.