I voted yes, but there are several variables that would determine whether I'd shoot or not. Obviously theseverity of the angle is the biggest factor, but if it were a slight quartering to angle I'd take the shot.Hard quartering to I'd pass. Also, it depends on the distance as well. If the deer were standing out past 25 yards and slightly quartering to I'd pass and wait to see if he presented me with a better shot angle.Inside 25 yards and slight quartering to, I'm shooting.JMO