RE: .204 ruger or .223 rem. ???
The 204 is not what I would buy. Unless you just want more guns.I allso would not go for a 22-250. If you want to shoot 400 yards go to a 243. they are a bigger bulet and the wind will not be as big facter.
I think the 223 is the best all around for yotes. Cheep bulets nice range. Many bulets to pic from.If you are going to shoot long shots with the 223 go to a 63 gr bulet.
charles bradford