I hunt witha 44mag and is the minimal I would use for deer. I won't hesitate for shots under 100 yards. I also have a 460Smith I used for the first time this year. And its basically has the power of the 45-70. Its shoots under 6" groups at 200 yards. Just amazing. I would have never thought that amount of accuracy could be had with a revolver.

I don't know of any semi I would ever take hunting. Maybe a 50AE with speicalized ammo.