I once took a nice 7 pointer.
I climbed up in a stand very late in the morning and grunted once. He got up out of the bed and came down the creek toward me. When he got behind a tree I pulled back. When he stepped across the creek I let fly. He just kind of jumped and continued to sniff the area for the scent I put out. I thought I had missed so I was reaching for another arrow. He then started shaking and ran about 10 ft and piled up. He never knew he was hit until it was WAY too late. That was awesome.
The arrow went directly though his heart.