If its mainly whitetail (being the largest 95% of the time) I would seriously consider a 7mm08. Very good round with less recoil. Many consider it the best whitetail caliber. Cost of ammo may be slightly more depending on where you are located in conjunction to sporting goods shops.

Never can go wrong with 270 just more recoil. Also remember with recoil there are ways to tame it. For instace the load you are using, weight of gun you purchase, simms limbsaver recoil pad, etc.

I also have a .243 and use it regularly for deer. No felt (to me at least) recoil at all. And you can use for varmit etc just not ideal for anything larger than whitetail.