The 22lr is more effective than the 25 acp, but not so with the others. Good hp ammo will outpreform a 22 rimfire any day by a large margin in the 32 or the 380. The Kel Tec 380 is often hard to find because so many police officers are buying them for backup, and by the way I think they can still be had for around $250 when you can find them. The Beretta models with the tip up barrel solve the problem of racking the slide,and also simplify unloading. I'm not trying to distract from the benefits of the revolver but only to give credit where credit is due. It's like learning to drive a car, everyone should have to learn in a stick shift, then they would be able to drive anything in an emergency!