What do you mean by .270 mag? Is it a .270 wsm, or a .270 weatherby mag? Or do you just mean a regular .270 win? I have a .270 win that I use sometimes for coyotes. I hand load 90gr Sierra varminter bullets for it, but you could use anything. DO NOT USE the 22. There isn't such thing as too much bullet for shooting predators unless you are trying to keep fur. The .270 would be your best choice. You can buy 100 gr loads made by Remington that would be good for predators.