NO. I've loaded and shot a lot of .357 and .44 shotshells and they are fantastic for snakes, birds, and very small vermin. But anything larger (cats, coons, opossums, dogs, etc.) and you're looking at a wounded animal making a huge mess. Those 50 pin pricks in their skin bleed a lot. Trust me on this one. And on a coon you may be looking at a very p@#$ed off animal.