"De gustibus non disputantum est". There's no accounting for taste is why!

If the biggest thing you will shoot is a coyote, there's no need for anything bigger than that .243. In fact, a .22 Hornet is plenty. However, if you want to destroy the evidence when shooting the neighbors' cats, use a .270 with 110-grain Sierras and 58 grains of IMR 4350 - I used to shoot jackrabbits and porcupines with this load, and all that was left of them was a hole in the air where they'd been, surrounded by a 6-foot diameter splash of blood in the center of the area. But the next rain takes care of that....... (I could actally watch them vanish in front of my eyes through the scope just before recoil obscured the scene.....)