A 54cal PRB with 90gr FFG will do when you get within 75yds. For the 50cal PRB you could do it. I would not get over 75yds though. I am sure it has been done and can will do just fine. Try the Baffalo ball-ets in that barrel. You can get them from www.possibleshop.com. Good luck with it and have a fun elk hunt!