RE: 150 yard groups open up
Just to add to your thoughts, Phil . . . . there are also certain muzzleloader bullets that just don't fly well at long range - even under calm conditions. The 200 yard group might be five times as big as the 100 yard group.
Others are very good. Like the 250 and 300 gr. Shockwave. If I get a 1.5" group at 100 yards, I usually get a 3 to 4" group at 200 yards.