The 50 BMG was designed as an anti material weapon. Meaning we have to aim at thier weapons or packs, instead of thier heads. So, can we really count it? I love all the cartridges that the 06' gave birth to. The only one i have not owned is a wildcat 6.5-06. The Whelen was built to kill big game like Elk and moose, using a 300gr bullet. Most factory barrels have the wrong twist to stabilize any thing larger than 250gr. Still, she packs a whallop. It will kill anything you desire to put an end to. I am not saying it is the perfect choice for walking into a thicket after a gut shot Grizzly. I wouldn't clamer for that honor, if i had a belt fed full auto 700 N.E. But, if you have asolidrest at reasonable range it will do the job. It has a stout little thump but it doesn't hurt like the magnums.