I've never loaded my '06 specifically for coyotes, have loaded plenty for groundhogs with 110 and 130 gr. bullets and have seen an accuracy edge with the 130s. It wouldn't be my recommendation to use either if you're looking to get nice pelts, very messy results with these lighter bullets. I don't know if they are still available, nor did they group that well out of my rifle, but the 55gr. accelerator would be perfect(55gr. sp@4000fps=lots of quick expansion without huge exit hole) If looking just to kill 'em, I'd go with 130 hp