The twist is important for hunting or long range target. For hunting on deer or larger and for extreme PRB range my choice after using all the calibers up to 72 would be the 54 I would get a twist of 1-66 to 1-80. There are several reasons for this,first it has to be available in a decant barrel length and twist for the caliber,then the recoil with a load [ 5/8 0f the ball weight will burn efficantly] has to be reasonableand for range you need the best sectional density and BC you can get. I was taking deer and bear at over 150 yds before we ever heard of sabots. The best choice I know of with out building your own or getting one custom built is the TC Hawken with a 32 inch 54 cal barrel from Foxridge,I dont know of any othe brand that makes one like this. if you get it custom made you want a 35 or 36 inch barrel. Lee