Everyones got an opinion, I only tried the 270 PPB since it was recommended to my dad by a #1 blackpowder shooter in NYS, although he also said 270gr was the min he would go. Myself, 270gr is the heaviest I have shot a deer with, most with 250gr shockwaves, and so far none have complained.
For me the choice is simple. Shoot what is most accurate in your gun. I probably wouldnt shoot something less accurate for any reason. If you can get great groupings with a multitude of rounds, then you can get picky. There are very few bullets out there that would have a problem taking a whitetail... elk and such is a different story perhaps. But I would wory about getting a nice tight group far before who recommends what, etc. I tried the 338 PB (the heaviest sold locally - and hard to find sometimes) in my cheapie CVA Staghorn trying to improve its accuracy. It did not group any better than the cheaper 250gr shockwaves. I ended up buying a new gun. And after doing some searching online I found that the even lighter 220gr all lead dead center sabots were recomended for my gun:
http://www.chuckhawks.com/knight_disc_elite.htm unfortunately they arent sold locally, I am going to try an order some in various weights and see how they perform next year, along with other sabots too. I havent yet found a bullet with accuracy I am happy with, if I dont this next year I may have to explore the possibility its the scope.