High hits from a steep angle, such as one from a treestand, can result in only catching one lung. Deer can travel several hundred yards on a one-lung hit, and some claim that deer can even survive these hits.

Another big problem is with a high hit (provided both entry and exit holes are high) is there is no "drain plug" as I like to call it -- instead of getting a great blood trail, the body cavity just fills up as the deer's adrenaline carries it the first 100-200 yards (again, assuming a high hit). Low hits often result in a deer incapable of going past 75, especially if you get both lungs.

Also, stay off the shoulder blade. Both deer I have lost in my career have been due to direct shoulder-blade shots. I trailed both after giving them at least eight hours, and oftentimes ended up on hands and knees trying to discern the path. I found both of those deer alive and well because I didn't penetrate into the body cavity. Six inches back and both of those deer would have been dead within sight.