I have a .243 and with 75 grain I hold a real tight group out to 400+ yards but I shoot mainly 100 grain my group is not as tight but still within an inch - I go with the 100 grains because it also doubles as my deer rifle and I like to shoot the same rounds out of it year round - no mess'n with the scope and I know where it is going to hit and when you're that accurate to 400 yrds on woodchucks and other varmints you sure as heck ought to be able to hit a deer