RE: antelope & coyote rifle
Another vote fr the 25-06 for what you want. There are other rounds that are good but IMHO the 25-06 is the best choice when taking into account availibility and performance out to 300 yards. Wally World to you're local shop odds are they'll have it in stock whick can't always be said about some rounds mentioned here and gets the nod over the 243 at longer ranges.