RE: Shot placement with a muzzleloader?
The deer anatomy doesn't change with the seasons so any shot that will kill a deer during the bow season will certainly kill it with a shotgun or rifle. Its a safe bet to make your point of impact just behind the shoulder so that both lungs are destroyed. There will be a thousand opinions from a 1000 hunters regarding point of aim but if you take out the lungs you'll cleanly and effectively harvest any anima that walks. You also have the benefit of little to no meat loss with this shot.
Good luck.