think of your bullet passing through as you would an arrow. With a hollow point I avoid massive bone structure. I like to tuck them behind the front leg where the elbow of the deer is. This shot, angled towards the other shoulder will take the top of the heart off, cut those arteries, blow the bottom of the lungs off, and make a good blood trail should they run off. Normally it plants them within 30 yards of where you hit them.