I havent shot any game with mine yet, but I have been reloading 240gr swc Meister bullets and have been very happy with the accuracy and thump that I am getting out of them. I am loading these with 21gr. or H110 powder, and have just loaded up some with 22gr to see if there is much difference. I know that at 50 yards they are penetrating clear through a 14 inch thick pitch stump and still throwing lots of dirt up behind them. I cant wait to try the gun out on a deer next year. I am shooting these out of a Marlin 1894 .44 Magnum rifle. I will be getting a 44 mag pistol in the near future, not sure which one but so far have been leaning towards a Taurus or Ruger.