I have a 270 and would trade it in a heartbeat for a 2506. Great deer cartridge and near perfect for antelope. Nothing wrong with a 270 win though with todays bullets better suited to tackle the bigger game but still not ideal. Yes I have shot antelope, deer, black bear, elk and moose withthe .270 win.My personal preference is a 7mm rem mag for the above, as bullet selection and limitations with the .284 are an advantage.