I used a 257wby for several years and took deer,mountain goat,elk and pronghorn with it.I handload and found that 100gr partitions worked well on allgame and ballistic tips worked well on deer and smaller animals.I would however not own one if I did not handload as ammo is very expensive and is not offered in many weights or styles of bullet.It can also be very difficult to find as most stores do not carry it.