The 25.06 is an awesome caliber. I know it's not the caliber of choice for Elk and i would personally use something bigger for that but i alsowouldn't be scared to shoot one with it using a well constructed bullet like the partition. You didn't say you were looking for an Elk rifle though you said antelope and from what i gather an antelope isn't that hard to kill. The 25.06 would be the perfect caliber for that type work. I've killed countless deer with my 25.06 over the years and it continues to be my caliber of choice when i'm deer hunting. It's pure deer poison around here and justabsolutely kills deer like lighting....period!Although i've never killed an antelope with it i have no doubt that it would have the same effect on those as well. My bullet of choice for my 25.06 is the 110gr Accubond, it's very accurate in my rifle and it's performance on deer has been excellent for me.This is only my opinion based on my experience with the 25.06 but if it's an antelope or deer rifle you want thenthe 25.06 is the ticket. Load that baby with a good 100-115gr bullet and rest assured, if you do your part it will get the job done and done quickly.

Just a side note. I've also killed lots of deer with my 30.06 and a Hornady 130gr SP. Let me add though that my longest shotwith this load was 294yds so i have no ideal how well it would perform beyond that range but i wouldn't be afraid to try it.This particulardeer fell in the scope when i squeezed the trigger and the bullet went through both shoulders and exited so it was well up to the task and i don't think the results could have been any better than that.