I spend alot of time on Winchester's and Federal's sites studying ballistics and have recently been looking at the difference (or lack of) between 243 and 25-06. I just find it ironic that many people put down 243 as a viable deer caliber, but the same people find 25-06 acceptable. Yes, there is a difference ballistically, but not enough to condemn one and praise the other. This is just my observation from reading on this site for a few years.