OlMossyhorns

Listen to Tifford,he has some good advice here,read the books he suggests,search for info on the calibers on the net,talk to the gunshops & people at your local shooting range if you can.

He is correct,if your bullets are passing through your overgunned or using the wrong bullets,all that does is waste meat,some of the bullets energy is wasted,you want it all used in the chest if possible.

All of the cals listed are accurate & have heaps of knockdown power.
25-06,270,280,30-06,260,7mm-08& 308,all would be suitable,however if you don't handload the 270,30-06 or 308 might be the best choice.
No need for magnums,you could even use a 243 if you place your shots very carefully & pass on ones that you are not able to place perfectly.
Remember if you over gun,your deer wont know the difference but it will cost you more money & waste meat.