Get a t-handle or palm-saver for your ramrod-end
Get a bore brush& large patches (2-1/2 or 3")
Swab after every 2nd shot
Buy thinner sabots like these below. If your bullets are .452, I usually try the Crush Ribs first. If they are .451, then I'll try the regular Harvesters first.
http://www.cabelas.com/products/Cpod0012633.jsp