I have about 7 people that I hunt with that use 06's (including myself till last year) and most of them have been hunting for over 20 years and have shot 150 gr. rem. corelocks for all that time and have never had any problems with them. That's what I used when I still used a 06 and what I use now with a 7mm-08 and every deer I shot was a one hit kill. I would say go with the 150 corelocks if you're just deer hunting and you shouldn't look back.